George and Judy Marcus Awards
Funding Cycle Awardees Announced!
The Marcus Program in Precision Medicine Innovation is pleased to announce the results of the 2017 call for innovative collaborative project proposals for the Seeding Bold Ideas and Transformative Integrated Research Initiatives. We received a total of 42 excellent and potentially transformative trans-disciplinary research proposals from faculty across UCSF. 21 cross-disciplinary teams submitted proposals to the Seeding Bold Ideas (SBI) Initiative and 21 teams submitted to the Transformative Integrated Research (TIR) Initiative.
A committee of researchers representing basic, clinical, and social/behavioral sciences reviewed, discussed, and selected 7 SBI projects and 3 TIR projects for funding.
The awardees for the 2017 Seeding Bold Ideas (SBI) Initiative are:
|
Team |
Proposal Title |
|
Chloe Atreya, MD/PhD Jean-Philippe Coppe, PhD Kevan Shokat, PhD |
Kinome-guided Targeted Therapy: Targeting Pro-Inflammatory Cascades in Patient-derived BRAF (V600E) Colorectal Cancer Xenografts |
|
Stephanie A. Christenson, MD/MAS Charles Langelier, MD/PhD Prescott G. Woodruff, MD/PhD |
Host/Pathogen Metagenomic Deep Sequencing for Precision Diagnosis of Acute Exacerbations of COPD |
|
Tien Peng, MD Stephanie A. Christenson, MD/MAS Prescott G. Woodruff, MD/PhD |
Single-cell Discovery Approach for Targeted Regenerative Therapy in Emphysema |
|
Neil Shah, MD/PhD Joseph DeRisi, PhD Margaret Fang, MD Ophir Klein, MD/PhD Art Weiss, MD/PhD |
The Molecular Medicine Consult Service: Bringing a Multidisciplinary Approach to Patients with Undiagnosed and Rare Diseases |
|
Dean Sheppard, MD Wendell Lim, PhD |
Engineering Lymphocytes to Treat Tissue Fibrosis |
|
Anthony Shum, MD Scott Oakes, MD Michael Waterfield, MD/PhD |
Targeting ER Stress and the Unfolded Protein Response as Treatment for the COPA Syndrome |
|
E. Alejandro Sweet-Cordero, MD Jonathan Weissman, PhD |
Enabling Functional Genomics and Precision Medicine in Pediatric Sarcomas Using Patient-derived Xenografts and Multiplexed Single-cell CRISPRi Screening |
The awardees for the 2017 Transformative Integrated Research (TIR) Initiative are:
|
Team |
Proposal Title |
|
Charles Chiu, MD/PhD Steve Miller, MD/PhD |
Precision Diagnosis of Acute Infectious Diseases |
|
Raymond Swanson, MD Caroline Tanner, MD/PhD Steven Finkbeiner, MD/PhD |
Toward a Redox-Directed Therapy for Parkinson’s Disease: Integrating Environmental, Genomic, and Functional Data |
|
Michael R. Wilson, MD/MAS Joseph DeRisi, PhD Samuel J. Pleasure, MD/PhD |
Precision Diagnosis of Autoantibody Mediated Encephalitis |