Marcus Program in Precision Medicine Innovation 2019 Awardees

George and Judy Marcus Awards

Marcus Program in Precision Medicine Innovation 2019 Awardees

The Marcus Program in Precision Medicine Innovation is pleased to announce the results of the 2019 call for innovative collaborative project proposals for the Seeding Bold Ideas, Transformative Integrated Research Initiatives and ELSI in Precision Medicine (ethical, legal, social implications). We received a total of 42 excellent and potentially transformative trans-disciplinary research proposals from faculty across UCSF. 20 cross-disciplinary teams submitted proposals to the Seeding Bold Ideas (SBI) Initiative, 17 teams submitted to the Transformative Integrated Research (TIR) Initiative and 5 teams submitted to ELSI in Precision Medicine.

A committee of researchers representing basic, clinical, computational health, and social/behavioral sciences reviewed, discussed, and selected 6 SBI projects, 3 TIR projects and 1 ELSI project for funding.

The awardees for the Marcus Program in Precision Medicine Innovation 2019 Seeding Bold Ideas (SBI) Initiative are:

Team

Proposal Title

Michael Evans, PhD
David Oh, MD, PhD

Developing functional imaging probes targeting granzymes to predict early tumor response to immune checkpoint protein inhibitors with positron emission tomography

David Pennington, PhD

An Vu, PhD

Tessa Rife, PharmD, BCGP

Dieter Meyerhoff, PhD

Steven Batki, MD

The neural basis of approach bias modification in opioid users with chronic pain

Elad Ziv, MD

Yin Shen, PhD

Inferring risk from rare variation in the human genome: applications to breast cancer risk

Charles Langelier, MD, PhD

Stephanie Christenson, MD, MAS

Integrated host/microbe metagenomics (iHMM) for precision diagnosis of sepsis

Mekhail Anwar, MD, PhD

Charles Craik, PhD

Molecular sensors for determining real-time efficacy of immunotherapies

Michael German, PhD

Ingrid Block-Kurbisch, MD

Susan Fisher, PhD

Michael McManus, PhD

Circulating placental exosomes as predictors of pregnancy outcomes

The awardees for the Marcus Program in Precision Medicine Innovation 2019 Transformative Integrated Research (TIR) Initiative are:

Team

Proposal Title

Charles Craik, PhD

Kimberly Kirkwood, MD

Kevan Shokat, PhD

Pamela Munster, MD

Targeting an intracellular oncoprotein in MHC I for immunotherapy with hapten-directed antibodies

Kate Rankin, PhD

Sergio Baranzini, PhD

Atul Butte, MD, PhD

Bringing deep biological knowledge networks into clinical practice at UCSF

William Weiss, MD, PhD

Luke Gilbert, PhD

David Raleigh, MD, PhD

Perturbing drivers of radiation resistance in glioblastoma

The awardees for the Marcus Program in Precision Medicine Innovation 2019 ELSI (Ethics, Legal and Social Implication) in Precision Medicine are:

Team

Proposal Title

Jalayne Arias, JD, MA

Jennifer Yokoyama, PhD

A collaborative model to genetic data-sharing guidelines in frontotemporal dementia

Marcus Program in Precision Medicine Innovation 2018 Awardees