George and Judy Marcus Awards
Marcus Program in Precision Medicine Innovation 2019 Awardees
The Marcus Program in Precision Medicine Innovation is pleased to announce the results of the 2019 call for innovative collaborative project proposals for the Seeding Bold Ideas, Transformative Integrated Research Initiatives and ELSI in Precision Medicine (ethical, legal, social implications). We received a total of 42 excellent and potentially transformative trans-disciplinary research proposals from faculty across UCSF. 20 cross-disciplinary teams submitted proposals to the Seeding Bold Ideas (SBI) Initiative, 17 teams submitted to the Transformative Integrated Research (TIR) Initiative and 5 teams submitted to ELSI in Precision Medicine.
A committee of researchers representing basic, clinical, computational health, and social/behavioral sciences reviewed, discussed, and selected 6 SBI projects, 3 TIR projects and 1 ELSI project for funding.
The awardees for the Marcus Program in Precision Medicine Innovation 2019 Seeding Bold Ideas (SBI) Initiative are:
Team |
Proposal Title |
Michael Evans, PhD |
Developing functional imaging probes targeting granzymes to predict early tumor response to immune checkpoint protein inhibitors with positron emission tomography |
David Pennington, PhD An Vu, PhD Tessa Rife, PharmD, BCGP Dieter Meyerhoff, PhD Steven Batki, MD |
The neural basis of approach bias modification in opioid users with chronic pain |
Elad Ziv, MD Yin Shen, PhD |
Inferring risk from rare variation in the human genome: applications to breast cancer risk |
Charles Langelier, MD, PhD Stephanie Christenson, MD, MAS |
Integrated host/microbe metagenomics (iHMM) for precision diagnosis of sepsis |
Mekhail Anwar, MD, PhD Charles Craik, PhD |
Molecular sensors for determining real-time efficacy of immunotherapies |
Michael German, PhD Ingrid Block-Kurbisch, MD Susan Fisher, PhD Michael McManus, PhD |
Circulating placental exosomes as predictors of pregnancy outcomes |
The awardees for the Marcus Program in Precision Medicine Innovation 2019 Transformative Integrated Research (TIR) Initiative are:
Team |
Proposal Title |
Charles Craik, PhD Kimberly Kirkwood, MD Kevan Shokat, PhD Pamela Munster, MD |
Targeting an intracellular oncoprotein in MHC I for immunotherapy with hapten-directed antibodies |
Kate Rankin, PhD Sergio Baranzini, PhD Atul Butte, MD, PhD |
Bringing deep biological knowledge networks into clinical practice at UCSF |
William Weiss, MD, PhD Luke Gilbert, PhD David Raleigh, MD, PhD |
Perturbing drivers of radiation resistance in glioblastoma |
The awardees for the Marcus Program in Precision Medicine Innovation 2019 ELSI (Ethics, Legal and Social Implication) in Precision Medicine are:
Team |
Proposal Title |
Jalayne Arias, JD, MA Jennifer Yokoyama, PhD |
A collaborative model to genetic data-sharing guidelines in frontotemporal dementia |